botulinum A toxin

botulinum A toxin
a powerful nerve toxin, produced by the bacterium Clostridium botulinum, that has proved effective, in minute dosage, for the treatment of various conditions of muscle dysfunction, such as dystonic conditions (see dystonia), including torticollis and spasm of the orbicularis muscle in patients with blepharospasm, and spastic paralysis associated with cerebral palsy; it is administered by injection. It may also be used to treat achalasia, being injected through an endoscope into the gastro-oesophageal sphincter, and is used in the bladder to treat urinary incontinence due to detrusor overactivity (as in multiple sclerosis) that is resistant to other treatments. Side-effects include prolonged local muscle paralysis.
Trade names:
Botox, Dysport.

The new mediacal dictionary. 2014.

Look at other dictionaries:

  • Clostridium botulinum C3 toxin — C3 exoenzyme Structure of Clostridium botulinum C3 exoenzyme NAD from PDB entry 2C8C [1] Identifiers Symbol …   Wikipedia

  • Botulinum toxin — Clinical data Pregnancy cat.  ? Legal status  ? (US) Rout …   Wikipedia

  • botulinum toxin — also botulinus toxin n a very powerful bacterial neurotoxin that acts primarily on the parasympathetic nervous system, is produced by botulinum, blocks release of acetylcholine at the neuromuscular junction, and causes botulism often used with… …   Medical dictionary

  • botulinum toxin type A — n a purified botulinum toxin of high molecular weight that is used by injection esp. to treat strabismus, blepharospasm, spasmodic torticollis, and severe axillary hyperhidrosis and in cosmetic dermatology and plastic surgery to minimize wrinkles …   Medical dictionary

  • botulinum toxin — toxin that causes the potentially fatal disease botulism and is found in spoiled food (created by the bacteria Clostridium botulinum which is used in biological weapons and in very small doses to treat muscular disorders) …   English contemporary dictionary

  • Botulinum-Toxin — Botulinumtoxin Serotyp A (Clostridium botulinum) Bändermodell nach …   Deutsch Wikipedia

  • Toxin — This article is about the class of poisonous substances. For other uses, see Toxin (disambiguation). Universal warning symbol used to indicate toxic substances or environments A toxin (from Ancient Greek: τοξικόν toxikon) is a poisonous… …   Wikipedia

  • botulinum toxin — Neurotoxin (50 kD; 7 distinct serotypes) produced by certain strains of Clostridium botulinum. The bacterium produces the toxin as a complex with a haemagglutinin that prevents toxin inactivation in the gut. Proteolysis in the body results in… …   Dictionary of molecular biology

  • botulinum toxin — noun any of several neurotoxins that are produced by the anaerobic bacterium Clostridium botulinum; causes muscle paralysis • Hypernyms: ↑neurotoxin, ↑neurolysin • Hyponyms: ↑botulinum toxin A, ↑Botox …   Useful english dictionary

  • botulinum toxin A — noun a neurotoxin (trade name Botox) that is used clinically in small quantities to treat strabismus and facial spasms and other neurological disorders characterized by abnormal muscle contractions; is also used by cosmetic surgeons to smooth… …   Useful english dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.