- botulinum A toxin
- a powerful nerve toxin, produced by the bacterium Clostridium botulinum, that has proved effective, in minute dosage, for the treatment of various conditions of muscle dysfunction, such as dystonic conditions (see dystonia), including torticollis and spasm of the orbicularis muscle in patients with blepharospasm, and spastic paralysis associated with cerebral palsy; it is administered by injection. It may also be used to treat achalasia, being injected through an endoscope into the gastro-oesophageal sphincter, and is used in the bladder to treat urinary incontinence due to detrusor overactivity (as in multiple sclerosis) that is resistant to other treatments. Side-effects include prolonged local muscle paralysis.Trade names:Botox, Dysport.
The new mediacal dictionary. 2014.
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botulinum toxin type A — n a purified botulinum toxin of high molecular weight that is used by injection esp. to treat strabismus, blepharospasm, spasmodic torticollis, and severe axillary hyperhidrosis and in cosmetic dermatology and plastic surgery to minimize wrinkles … Medical dictionary
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botulinum toxin — Neurotoxin (50 kD; 7 distinct serotypes) produced by certain strains of Clostridium botulinum. The bacterium produces the toxin as a complex with a haemagglutinin that prevents toxin inactivation in the gut. Proteolysis in the body results in… … Dictionary of molecular biology
botulinum toxin — noun any of several neurotoxins that are produced by the anaerobic bacterium Clostridium botulinum; causes muscle paralysis • Hypernyms: ↑neurotoxin, ↑neurolysin • Hyponyms: ↑botulinum toxin A, ↑Botox … Useful english dictionary
botulinum toxin A — noun a neurotoxin (trade name Botox) that is used clinically in small quantities to treat strabismus and facial spasms and other neurological disorders characterized by abnormal muscle contractions; is also used by cosmetic surgeons to smooth… … Useful english dictionary